Link your favorite Python conference talk and give everyone else a chance to be blown away like you were the first time you heard it!

Please also include some description of what you liked about the talk. Also, the only requirement is that it is at least tangentially related to Python, so talks about developing in Python, developing CPython, general programming techniques that also apply to Python, some Python library, or even the community are all fair game.

Also, feel free to submit more than one talk, but please include only one talk per top-level comment so that we can have a place to discuss each one.