Thanks in part to Elon Musk, the field of brain-computer interfaces has captured both public and investor interest, with a cadre of companies now developing implantable devices.

In September, Elon Musk’s brain-implant company Neuralink announced the much-anticipated news that it would start recruiting volunteers for a clinical trial to test its device. Known as a brain-computer interface, or BCI, it collects electrical activity from neurons and interprets those signals into commands to control an external device. While Musk has said he ultimately wants to merge humans with artificial intelligence, Neuralink’s initial aim is to enable paralyzed people to control a cursor or keyboard with just their thoughts.

Rival efforts to connect people’s brains to computers are also moving forward. This year, Neuralink competitor Synchron demonstrated the long-term safety of its implant in patients. Other startups tested novel devices in human subjects, while new ventures came on the scene.

“It can definitely feel like a breakout year, but in fact it’s the result of decades of work in academia,” says Sumner Norman, a visiting researcher at the California Institute of Technology who’s also the cofounder and CEO of Forest Neurotech, which launched in October. “I think we’re really just starting to feel the effects of that exponential growth.”

The origins of BCIs stretch back to the 1960s and 1970s, when the first ones were tested on lab animals. As researchers began to understand the brain better, these systems evolved to be more sophisticated, allowing paralyzed people to move robotic arms, play video games, and communicate with their minds. Once a largely academic pursuit, BCIs are now of interest to a growing cadre of companies that have emerged since Neuralink’s founding in 2016.

  • @[email protected]
    5•6 months ago

    Like, I have a lot of trust and confidence in the science…

    You shouldn’t.

    Animal Testing Mess (click to read)

    The mistakes leading to unnecessary animal deaths included one instance in 2021, when 25 out of 60 pigs in a study had devices that were the wrong size implanted in their heads, an error that could have been avoided with more preparation, according to a person with knowledge of the situation and company documents and communications reviewed by Reuters.

    The mistake raised alarms among Neuralink’s researchers. In May 2021, Viktor Kharazia, a scientist, wrote to colleagues that the mistake could be a “red flag” to FDA reviewers of the study, which the company planned to submit as part of its application to begin human trials. His colleagues agreed, and the experiment was repeated with 36 sheep, according to the person with knowledge of the situation. All the animals, both the pigs and the sheep, were killed after the procedures, the person said.

    Kharazia did not comment in response to requests.

    On another occasion, staff accidentally implanted Neuralink’s device on the wrong vertebra of two different pigs during two separate surgeries, according to two sources with knowledge of the matter and documents reviewed by Reuters. The incident frustrated several employees who said the mistakes – on two separate occasions – could have easily been avoided by carefully counting the vertebrae before inserting the device.

    Company veterinarian Sam Baker advised his colleagues to immediately kill one of the pigs to end her suffering.

    “Based on low chance of full recovery … and her current poor psychological well-being, it was decided that euthanasia was the only appropriate course of action,” Baker wrote colleagues about one of the pigs a day after the surgery, adding a broken heart emoji.

    • SaltySalamander
      2•6 months ago

      In other words, human error. That wasn’t what the person you responded to was talking about when they said they trust the science.