Seems that trials are already happening. As a person living with UC, this could be a game changer.
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Sounds too good to be true. Let’s hope it’s real.
I’m sure it will be, just in time for some global apocalypse to render it a moot point.
In fairness, I’d rather deal with an apocalypse whilst not living with pemphigus, so if I remain incredibly fortunate, I’d love to give it a go if it passes phase IVs
Is there any tldr of which diseases this helps with?
TLDR would be that any autoimmune disease could see this helping. It “removes/erases” the white blood cells memory of the bodily molecule that we don’t want destroyed from their list of things to destroy.
That’s incredible, and revolutionary if it works. I wonder if allergies will ever be treated in this way aswell
With my beginner understanding of the immune response, they could if this is successful. Since allergies are the immune response to an external stimuli instead of an internal stimuli like an autoimmune disorder.
Thank you! That sounds like amazing progress, between this and CRISPR’s progress with cancer, the future looks good for anyone suffering from these
Too late for me, but good news for those who come after.
God dammit, after I have my colon removed.
You and me both friend.
That sounds amazing. I hope it all works out
If this works out it would be a game changer, though most likely also priced as such especially if it is a one hit solution for diseases such as MS as there is a lot of money being made out of the current medication, hopefully it doesn’t get buried.
This might even work with allergies then!
Icahn. Sounds like a silver bullet. Hope it’s true.
How does one keep up with developments on something like this?
It’s be a bit premature to do that, if you’re interested as a patient or layperson. It will also be all over the news in five years or so if it works and they bring it to market.
However, it looks like you could make an alert for the company name (Anokion SA) if you’re interested.
Those trials are conducted by the pharmaceutical company Anokion SA, which helped fund the new work and which Hubbell cofounded and is a consultant, board member, and equity holder
@baruchin The technology seems relatively simple and low-risk: tag a molecule with a specific sugar… I wonder if this is something biohackers can manage to do before clinical trials and Big Pharma approval. If so, sign me up! #biohacking
In mice
Not tonight, Pinky…
phase I safety trials have already been carried out in people with celiac disease, an autoimmune disease that is associated with eating wheat, barley, and rye, and phase I safety trials are underway in multiple sclerosis.
I know, I know. Safety studies do not judge the effectiveness, but at least they’ve actually moved on from mice to humans this time.
This!
