I mean, I’m not an expert in dealing with trans people, but these kinds of “awkward rare person type” interactions have a really safe way of dealing with it : don’t fucking mention it until they do, then be polite about it and ask if you can “learn more”.

I really shoved my foot in it once when I worked with someone who was a drummer , where I had problems with my left hand playing at home on my kit, and they were interested in joining a jam. “Oh you’re a drummer, how do you deal with having your weaker hand being slower? I really suck at it”.

Then much later that day (or week) I realised they had ectrodactyly, and I died of shame, I am now a ghost.