TOS: City on the Edge of Forever - Written by Harlan Ellison with Joan Collins as Edith Keeler.

It looks like it is (not surprisingly) already starting to be considered. https://www.macrumors.com/2023/06/15/reddit-threatens-to-remove-subreddit-moderators/

What was the magic hypo serum they used? Was it the lost Captain America serum? Or has that been referenced / used before somewhere else in universe that I don’t recall?