cross-posted from: https://piefed.world/c/depression_now/p/933723/does-anybody-else-s-anti-depressants-wear-off-after-taking-a-nap-or-otherwise-sleeping

Duloxetine works great for me until I sleep, then I wake back up into the pit of despair and I feel like I’m supposed to wait until ~24 hours since I last took it in order to take it again. I can’t find any cases of other people reporting this and it’s not something my medical professionals have heard of. It makes it hard if I don’t have energy due to not getting enough sleep the night before so I take a nap, and then when I wake up I still don’t have energy due to lack of willpower. I’ve also found it harder to get out of bed in the morning shortly before taking the medicine.

  • emotional_soup_88English
    2·
    2 天前

    If you need Duloxetine in order to sleep, then I don’t know… Otherwise, I do this: I take Sertraline in the morning when I wake up and it last the whole day. Then, when I need to sleep - and if I’m unable to sleep because kdw anxiety - I take Zoplicone, which knocks me out. It’s not an antidepressant nor is it ani anxiety medicine, it just induces sleep.